COMPARISON OF MUSCLE STRENGTH, AEROBIC CAPACITY AND BODY COMPOSITION BETWEEN HEALTHY ADOLESCENTS AND THOSE LIVING WITH HIV: A SYSTEMATIC REVIEW
Physical fitness, pediatrics, Human immunodeficiency virus.
Background: Adverse effects of antiretroviral therapy associated with complications generated by HIV promote impairments in physical fitness in adolescents. Objective: analyzing the aerobic capacity, muscle strength and body composition of adolescents living with HIV compared with a healthy population of the same age. Methods: Searches were performed in the MEDLINE, Embase, Web of Science, Scopus and SportDiscus databases until September 2019. Eligibility Criteria: adolescents of both sexes in the age group from 10 to 19 years; living with HIV; cross-sectional, case-control, cohort studies; comparing with a healthy population of the same age group; Inter-reviewer's agreement was calculated using the Kappa index for each phase of article selection (kappa = 0.74). Results: 5 articles were included, involving 197 adolescents living with HIV and 185 without infection, with sample in each study ranging from 15 to 65 adolescents. The HIV group ranged from 16 to 18 years and the age between healthy controls ranged from 13 to 18 years. Aerobic capacity and muscle strength were reduced in adolescents with HIV, and body mass index was significantly lower in this group. Conclusion: adolescents living with HIV have impaired cardiorespiratory fitness and muscle strength, as well as a lower body mass index when compared to the uninfected population in the same age group. However, none of the included studies showed a good methodological quality. Additional studies are needed to define which strategies can be applied to improve the physical capacity and body composition of HIV-infected adolescents. The protocol for this review was registered in the PROSPERO database under code CRD42019140955.