Banca de DEFESA: BRENDA SANTOS LEITE

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : BRENDA SANTOS LEITE
DATE: 29/04/2022
TIME: 14:00
LOCAL: Virtual
TITLE:

Incidence of intestinal parasites in cancer patients treated at a referral center in Rio Grande do Norte.

KEY WORDS:

cancer, immunosuppressed patients; intestinal parasites; cancer treatment; symptomatology.

PAGES: 90
BIG AREA: Ciências Biológicas
AREA: Parasitologia
SUMMARY:

Several studies have reported the incidence of opportunistic intestinal parasites in populations of immunosuppressed patients, in patients undergoing hemodialysis, in transplant recipients and in those with autoimmune diseases. However, there is little information about these parasites in cancer patients submitted or not to cancer treatment. Thus, the objective was to evaluate the incidence of intestinal parasites in cancer patients treated at a referral center in Rio Grande do Norte, in order to show whether there is a relationship between their presence, the patient's health status and the completion of cancer treatment, in addition to establishing an association with their social, economic and behavioral characteristics. For this, fresh stool samples were requested from 67 cancer patients aged 18 years or older, who were diagnosed with cancer, undergoing or not to chemotherapy and that signing the “Termo de Consentimento Livre e Esclarecido (TCLE)”. The samples were submitted to the Holfmann, Pons and Janer (HPJ), Willis and Rugai, methods to determine the presence of intestinal parasites and a questionnaire was applied on the socio-economic aspects, food and hygiene habits and chemotherapy and parasitological information of the patients. The collected data were analyzed using descriptive statistics (position measures (median and mode), absolute and relative frequencies), contingency tables and Chi-Square test, in the R ® software [R Core Team (2021)]. The positivity of the stool parasitological exams was 56,7%, with 74.2% being characterized as monoparasitic infection and 25.8% as multiple infection. Endolimax nana (36,8%) and Entamoeba coli (34,2%) were prevalent, followed by Entamoeba histolytica, Giardia lamblia, Hymenolepis spp. and hookworms. The age group most affected by parasitism was 30 to 59 years old, female, and undergoing cancer treatment. Regarding the type of cancer, 87% of parasitized patients had breast cancer concomitant with polyparasitism. There was a relationship between the oncological treatment and the presence of nausea symptoms (p<0.05) in the parasitized patients, however, no association was identified between the parasitism and the other factors evaluated in the questionnaire (p>0.05), concluding that the infection of the patients regardless of whether or not the patient is undergoing cancer treatment and whether he has symptoms such as vomiting and/or diarrhea.

BANKING MEMBERS:
Externo ao Programa - 1282620 - HENRIQUE ROCHA DE MEDEIROS
Interna - 1714262 - LILIAN GIOTTO ZAROS DE MEDEIROS
Externa à Instituição - LUÍSA MOURÃO DIAS MAGALHÃES - UFMG