Banca de DEFESA: LUÍS EDUARDO BARBALHO DE MELLO

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
DISCENTE : LUÍS EDUARDO BARBALHO DE MELLO
DATA : 19/07/2019
HORA: 08:30
LOCAL: Departamento de Nutrição
TÍTULO:

 

Genomic Study for Risk Loci Identification for Familial Non-Spinal Thyroid Carcinoma

PALAVRAS-CHAVES:

Non-marrow familial carcinoma, Papillary carcinoma, Genes, Pathogenesis

PÁGINAS: 52
GRANDE ÁREA: Ciências da Saúde
ÁREA: Medicina
RESUMO:

The incidence of differentiated carcinomas in Rio Grande do Norte, Brazil, is relatively high. Casually, we observed a remarkable occurrence of cases of papilliferous carcinomas in members of the same families identified in our series, based on routine clinical observations. In some families we detected three or more cases of papillary carcinomas diagnosed between first and second degree relatives. Thus, we decided to deepen the study regarding the etiopathogenesis of these tumors in order to establish if there is any expression among these individuals, that can justify such a prevalence and to draw a clinical and molecular profile from the analysis of the exoma sequencing through a study of DNA extracted from collections of blood samples from these patients and their relatives. With the information generated by the new generation genetic sequencing, indicating genes associated with differentiated thyroid carcinoma, it will be possible to improve the diagnosis, treatment and tracking of family members affected by thyroid nodular disease, impacting on the various indices of gauging the results of health promotion. This project is original since it addresses a research topic not yet clarified in the literature and unpublished in our country.

MEMBROS DA BANCA:
Externa à Instituição - ADRIANA BEZERRA NUNES - UFPB
Interna - 1199080 - ANA KATHERINE DA SILVEIRA GONCALVES DE OLIVEIRA
Externa à Instituição - JANETE MARIA CERUTTI - UNIFESP
Externa à Instituição - PAULA FRASSINETTI VASCONCELOS DE MEDEIROS - UFCG
Externa ao Programa - 2261797 - TIRZAH BRAZ PETTA LAJUS