Banca de DEFESA: EDIENNE ROSANGELA SARMENTO DINIZ

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : EDIENNE ROSANGELA SARMENTO DINIZ
DATE: 24/05/2022
TIME: 09:30
LOCAL: Remoto
TITLE:

ANALYSIS OF THE EFFECT OF THE STANDARDIZATION OF MEASURES TO PREVENT BLOOD CURRENT INFECTION RELATED TO THE CENTRALLY INSERTED CATHETER IN NEWBORNS IN THE NEONATAL INTENSIVE CARE UNIT

KEY WORDS:

Peripherally Inserted Central Catheter; Peripheral Catheterization; Risk factors; Catheter-Related Infections; Newborns; Neonatal Intensive Care Unit.

PAGES: 242
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Introduction: The use of peripherally inserted central catheters (PICC) in neonatology has significantly contributed to the reduction of neonatal mortality in neonatal intensive care units (NICUs). This safe intravenous practice favors the hemodynamic stabilization of the newborn, allows the administration of vesicant drugs, irritants and parenteral nutrition (PN). Thus, this study aims to evaluate the effect of standardization of infection prevention measures during insertion and handling of peripherally inserted central venous catheters (PICC) by the catheter team on the incidence of CRBSI in newborns in the Unit of Neonatal Intensive Care. Methodology: it is divided into three studies. 1) Systematic review protocol, which addresses the prevalence of complications associated with the use of PICCs in newborns (NBs); 2) prospective cohort to assess risk factors for the development of catheter-related bloodstream infection (CRBIS) in newborns; 3) cohort with retro and prospective analysis, which will analyze the effect of standardization of infection prevention measures adopted by the PICC team on the number of CRBSI cases in neonates in the Neonatal Intensive Care Unit. Results: in article 1, the prevalence of complications resulting from the inadequate management of the PICC in NBs was observed, information considered important for the improvement of clinical practice. In article 2, it was found that the majority of the sample consisted of premature infants, with inadequate weight, respiratory disorders and heart disease, but there was no association of these variables with CRBSI. Neonates with PICC in the upper limbs had a higher risk of CRBSI (RR=2.84; 95%CI 1.02-6.85). Article 3 analyzed 365 newborns who used the PICC, who underwent 563 catheter insertion procedures, of which 69 had CRBSI, giving an incidence of CRBSI of 12.3%. In the analysis of characteristics related to the PICC insertion procedure in neonates as a result of CRBSI notification, the variables significantly associated with the occurrence of CRBSI were the vessel accessed (p=0.002) and catheter position (p=0.005). In the statistical analysis of the variables related to infusion therapy, statistical significance was observed in the association between the occurrence of CRBSI and the use of two ATBs during the first antibiotic therapy regimen, which presented a value of p<0.05. There was also a description of 8 groups of pathogens involved in 69 cases of CRBSI, with the most common pathogens related to CRBSI in newborns with PICC being the Enterobacteria (5.2%), Staphylococcus coaEnterobacteria (5.2%), Coagulase negative Staphylococcus (3.4%) and coagulase positive Staphylococcus (2.0%). Conclusion: the importance of catheter teams in the systematization of the monitoring process of risk factors related to the NB, surveillance during the procedure, and infusion therapy was observed. Such measures have impacted on reducing the development of catheter-related bloodstream infection (CRBIS).

BANKING MEMBERS:
Presidente - 1149540 - ANGELO GIUSEPPE RONCALLI DA COSTA OLIVEIRA
Interna - 2568454 - ELISANGELA FRANCO DE OLIVEIRA CAVALCANTE
Externa ao Programa - 3168491 - NILBA LIMA DE SOUZA
Externo à Instituição - AUREAN DECA JÚNIOR - UFMA
Externa à Instituição - KÁTIA SUELY QUEIROZ SILVA RIBEIRO - UFPB
Externa à Instituição - RITA DE CÁSSIA SILVEIRA - UFRGS