Banca de DEFESA: CAROLINE FERREIRA SCHON

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : CAROLINE FERREIRA SCHON
DATE: 04/03/2024
TIME: 08:30
LOCAL: presencial
TITLE:

Effects and safety of early cardiac rehabilitation on cardiac function and functional capacity after acute myocardial infarction

KEY WORDS:

Acute myocardial infarction; Cardiac rehabilitation; Exercise dose;

PAGES: 157
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

Inglês Introduction: Exercise-based cardiac rehabilitation (CR-ex) is a non-drug procedure already clinically incorporated with a grade AI recommendation for post-acute myocardial infarction (AMI) patients in the outpatient phase. Despite the scientific UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE CENTRO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM FISIOTERAPIA Av. Campus Universitário – Lagoa Nova - Natal-RN, CEP 59078-970 Telefax: (84) 3342-2003 E-mail: ppgfis@ufrn.br growth of RC-ex in the hospital phase and early after the event, its efficacy and safety require clarification with more robust methodological designs. Objective: To analyze the effectiveness of a CR-ex protocol on physical demand and cardiac function, in addition to cardiohemodynamic safety after recent AMI. Materials and methods: Inpatients with AMI and successful percutaneous coronary intervention (PCI) were included in the clinical trial and planned in two groups: Intervention Group (IG) and Control Group (CG). Both groups received the initial phase of in-hospital RC-ex, optimized drug treatment and guidance for self-managed ambulation, however, the GI continued RC-ex with progression in the in-hospital phase and the semi-supervised home phase. Participants underwent the same clinical and functional assessments, with maximal and submaximal physical effort tests (ergometer test and 30s sit-tostand test) and heart rate variability (HRV) analysis. Results: Chapter 1 presents the publication of the protocol of this clinical trial in the journal Plos One. Chapter 2 contains the validation of the theoretical content of the RC-ex protocol. In Chapter 3, a longitudinal analysis carried out during the pilot study obtained low rates of adverse events in 129 RC-ex sessions, even with significant increases in heart rate, systolic blood pressure and the double product, immediately after the sessions. Chapter 4 describes the clinical trial that showed a significant increase in HRV indices (SDNN, RMSSD, SD1 and HF) in the IG compared to the CG in the reevaluation. The physical collection evaluated by ET showed an increase of 2.07 MET's in the IG compared to the CG, however, without a statistically significant difference. The 30s Sit and Stand Test (TSL 30s) showed a similar increase between the groups with no statistical difference. Conclusion: RC-ex with an estimated final dose of 845 METmin after AMI was effective in improving cardiac autonomic balance. This study provides important guidance on a safe and effective therapeutic window for early CRex in patients with AMI

COMMITTEE MEMBERS:
Externa à Instituição - AMANDA SOARES FELISMINO SILVEIRA
Externa à Instituição - RENATA CARLOS FELIPE - UFRN
Externa à Instituição - RENATA CRISTINA CORTE
Presidente - 1149619 - SELMA SOUSA BRUNO
Interna - 2319151 - TATIANA SOUZA RIBEIRO