Banca de QUALIFICAÇÃO: CAROLINE FERREIRA SCHON

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : CAROLINE FERREIRA SCHON
DATE: 31/10/2023
TIME: 09:00
LOCAL: Presencial - sala 8 do Departamento de Fisioterapia
TITLE:

Efficacy of Early Cardiac Rehabilitation after Acute Myocardial Infarction: Randomized Clinical Trial

KEY WORDS:

Cardiac rehabilitation; Myocardial infarction; Physical Fitness; 

PAGES: 56
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

Exercise-based cardiac rehabilitation (CR) is a non-drug procedure already clinically incorporated with a grade AI recommendation for patients after acute myocardial infarction (AMI). However, such evidence comes from studies at later stages after the cardiac event. CR in the hospital phase and early in the event has grown in the last decade, but its efficacy and safety during the procedure need to be clarified with more robust methodological designs. Thus, the objective of this study is to analyze the effectiveness of a CR protocol based on physical exercises on physical fitness, morphology and cardiac function, in addition to cardiohemodynamic safety in hospitalized patients with recent AMI. A controlled and randomized clinical trial will be carried out at the Hospital Universitário Onofre Lopes (HUOL) with a CR protocol based on early physical exercise (>8 hours of clinical stability) for patients with AMI who have successfully undergone percutaneous coronary intervention (PCI). After randomization, patients will be grouped into IG and CG (intervention and control), both underwent an early mobilization routine and walking guidance, however, only the IG underwent the CR protocol based on periodized physical exercises for the hospital phase. Subjects in both groups will undergo the same functional assessments, maximal and submaximal (cardiopulmonary and 30s sit-up tests), cardiac magnetic resonance imaging and analysis of heart rate variability. Preliminary results obtained from 27 patients on safety and cardiohemodynamic changes reveal that in-hospital CR presented only 5.4% of adverse events during 111 sessions and a significant increase in heart rate (p=0.001) and the double product ( p=0.003) as an immediate effect of the exercise session. It is expected to observe at the end of the study the positive effect of in-hospital CR on cardiac structure and function and its clinical impact on increasing physical fitness, allowing greater understanding of the variables of exercise prescription and their physiological responses to predict therapeutic strategies more efficient and earlier during the in-hospital rehabilitation process in patients with AMI.

COMMITTEE MEMBERS:
Presidente - 1149619 - SELMA SOUSA BRUNO
Externa à Instituição - AMANDA SOARES FELISMINO SILVEIRA
Externa à Instituição - RENATA CARLOS FELIPE - UFRN