Banca de DEFESA: ALAN MICHEL BEZERRA FURTUNATO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : ALAN MICHEL BEZERRA FURTUNATO
DATE: 17/03/2020
TIME: 09:00
LOCAL: Sala do Pop-RN - Centro de Convivência, UFRN
TITLE:

Electrophysiological characterization of the delta and theta oscillations of the dorsal hippocampus of rats during running on a treadmill

KEY WORDS:

Hippocampal oscillations; delta; theta; treadmill running.

PAGES: 120
BIG AREA: Ciências Humanas
AREA: Psicologia
SUMMARY:

The hippocampal theta rhythm (6-10 Hz) was extensively studied along the literature and has involved with cognitive functions, sensory-motor integration, paradoxical sleep and locomotion. And was well characterized along the septo-temporal hippocampal axis. However, the delta rhythm (0.5-4 Hz), commonly investigated on the slow-wave sleep, inactivity, anesthesia and epilepsy seems to be widespread over multiple cortical and subcortical areas as theta oscillations. What is coherent with the literature, once that slow frequency oscillations allow the exchange of information of neuronal assemblies between distant brain areas. In the present work, we proposed an electrophysiological characterization of theta and delta oscillations through two distinct locomotion protocols on a treadmill, on the hippocampal area of CA1 dorsal of rodents. In the first manuscript, we take data of the electrophysiological register of 3 long-evans male rats submitted to 11 sessions (n=11) of 35 runnings of 15 s at 30 cm/s on a maze task. Where we observed an increase and a gradual decrease of the delta and theta power, respectively across the runnings. Beyond that, an increase of the interhemispheric phase coherence of the delta band. Next, on the second manuscript, we take electrophysiological registers of the local field potential in 6 male rats of wistar lineage on 22 sessions (n=22) of 48 bouts of 20 s on 3 accelerated speeds (1, 1,5 and 2cm/s) and 3 constant speeds (20, 30, 40 cm/s) escalated on a sequence of 8 blocks of 6 runs. Trough these protocols we verified that delta oscillations showed an increase of power meanwhile theta oscillations showed a power decrease along of the runnings. Yet, the hippocampal delta oscillation of rodents showed a significative increase in power and frequency on runnings at highest speed. Together, our results suggest that the hippocampal delta oscillation has function on the physiological condition signaling of the experimental subject, which could serve as a signaling parameter of the fatigue levels on rodents along of successive runnings.

BANKING MEMBERS:
Presidente - 1696755 - BRUNO LOBAO SOARES
Externo à Instituição - CLEITON LOPES AGUIAR - UFMG
Externo ao Programa - 1989744 - HASSAN MOHAMED ELSANGEDY