Banca de DEFESA: MARIA ELISA LEITE FERREIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MARIA ELISA LEITE FERREIRA
DATE: 16/03/2020
TIME: 09:00
LOCAL: Sala Darwin
TITLE:

Behavioral differences in the response to alcohol in juveniles of zebrafish (Danio rerio).

KEY WORDS:

Ethanol; Personality; Zebrafish; Metabolism; Egg emergence; Behavior; Anxiety.

PAGES: 47
BIG AREA: Ciências Humanas
AREA: Psicologia
SUMMARY:

Alcohol (ethanol or ethyl alcohol) is undoubtedly the most widely used legal drug of abuse in the world. The excessive use of this substance can cause alcoholism, one of the most devastating diseases among those related to drugs of abuse. The reinforcing effects of moderate alcohol use are the result of the interaction with neurotransmitter systems such as, for example, dopamine (DA), serotonin (5HT), gamma-aminobutyric acid (GABA), and glutamate, and neuromodulator systems such as adenosine. However, we know that some individuals are more sensitive to the effects of alcohol while others are more resistant, a response that may be related to genetic and environmental / social factors. Determining the relationship between the behavioral profile and alcohol use is difficult, since both the individual's behavioral and neurophysiological analysis must be taken into account. In order to better understand the above cited aspects of alcohol consumption, the zebrafish has become a promising model animal, because it offers the chance to investigate alcohol and individual differences effects, it presents classic vertebrate neurotransmitters, and shows high genetic similarity with humans. Another advantage is the well-known behavioral repertoire derived from zebrafish alcohol exposure, which also shows similarities to human behavior. In this sense, this work evaluated through behavioral tests whether individual differences established early in life can be predictive of the effects of alcohol consumption.

BANKING MEMBERS:
Presidente - 1644341 - ANA CAROLINA LUCHIARI
Externo à Instituição - CARLA DENISE BONAN - PUCRS
Externa ao Programa - 1720860 - VANESSA DE PAULA SOARES RACHETTI