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Banca de QUALIFICAÇÃO: TÁSSYO LEANDRO DA SILVA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : TÁSSYO LEANDRO DA SILVA
DATE: 22/03/2023
TIME: 09:00
LOCAL: Link de acesso para videoconferência: https://meet.google.com/yxz-ugvj-jur
TITLE: Applicability and antioxidant activity of Prosopis juliflora extract as a multifunctional cosmetic raw material

KEY WORDS:

Mesquite; Prosopis juliflora; Antioxidant; Cosmetics; Melanogenesis.

PAGES: 98
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

The rich biodiversity of plant species in Brazil encourages studies with plants for the

development of products containing natural compounds. P. juliflora, popularly known

as algaroba, is a plant that was brought from Peru, introduced and spread through the

semi-arid region of the Northeast and, becoming an invasive species in the Caatinga.

Studies report antimicrobial, antioxidant, antimalarial, antitumor actions, among others,

due to the presence of secondary metabolites such as alkaloids, terpenoids, tannins

and flavonoids, present in different parts of this plant. Some of these metabolites can

be used by the cosmetic industry with different activities. This work aims to evaluate

the antioxidative and antityrosinase activity of the P. juliflora fruit extract and to develop

cosmetic formulations for harmonizing skin color. For that, the extract obtained by

previously standardized methodologies was evaluated for the concentration of total

flavonoids, which showed concentrations of 1.71 ± 0.26 µg EQ/mg and 0.21 ± 0.01 mg

GAE/g of phenolic compounds. In addition, the extract was obtained by previously

standardized methodologies and the antioxidant activity in vitro was evaluated by

different methodologies: scavenging of superoxide radicals and 2,2-diphenyl-1-

picrylhydrazyl (DPPH), total antioxidant capacity, reducing power, chelation of metal

ions (Cu2+ and Fe2+) and superoxide anion radicals (O2-), and the antioxidant activity

of the lyophilized extract was observed. The in vitro safety of the extract was performed

through cytotoxicity tests and the samples did not show cytotoxic effects. The samples

have not yet shown to have an antimelanogenic action, but new tests are needed to

elucidate this activity. This project, in addition to contributing scientifically by

demonstrating the use of a Caatinga plant in anti-melanogenic cosmetic products, will

also contribute to adding value to the P. juliflora production chain, aiming to enhance

aspects of environmental and social responsibility and Brazilian biodiversity.

COMMITTEE MEMBERS:
Externa à Instituição - CASSIARA CAMELO ELOI DE SOUZA - UFBA
Externo à Instituição - ANDRE LEANDRO SILVA - UFOB
Presidente - 3652554 - FRANCISCO CANINDE DE SOUSA JUNIOR

Notícia cadastrada em: 27/02/2023 15:04