Banca de QUALIFICAÇÃO: KATIUSSE ALVES DOS SANTOS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : KATIUSSE ALVES DOS SANTOS
DATE: 09/06/2021
TIME: 10:00
LOCAL: Link de acesso para videoconferência: https://meet.google.com/uvm-izmk-rcn
TITLE:

Circulating Exosomal miRNAs as Biomarkers for the Diagnosis and Prognosis of Colorectal Cancer

KEY WORDS:

colorectal cancer; biomarkers; exosomal; miRNAs; circulating.

PAGES: 47
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

Colorectal cancer (CRC) is one of the most common malignant tumors in the gastrointestinal tract. It is a multifactorial disease that involves environmental, genetic and lifestyle factors. Due to the absence of specific and sensitive biomarkers, CRC patients are usually diagnosed at an advanced stage and consequently suffer from a low 5-year overall survival rate. Despite improvements in surgical resection and adjuvant chemotherapy, the prognosis of patients with CRC remains unfavorable due to local and distant metastases. Several studies have shown that small noncoding RNAs, such as microRNAs (miRNAs) packed in exosomes, are potential biomarkers in various types of cancers, including CRC, and that they can be detected in a stable form in both serum and plasma. In this review, we report the potential of circulating exosomal miRNAs to act as biomarkers for the diagnosis and prognosis of CRC.

BANKING MEMBERS:
Presidente - 2323511 - ADRIANA AUGUSTO DE REZENDE
Interna - 1055045 - MARCELA ABBOTT GALVAO URURAHY
Externo ao Programa - 2492744 - ROMUALDO DA SILVA CORREA