Banca de QUALIFICAÇÃO: VALDJANE SALDANHA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE : VALDJANE SALDANHA
DATA : 26/06/2019
HORA: 09:00
LOCAL: SALA 2 DO PPGCF
TÍTULO:

PREVISÃO DE PROBLEMAS RELACIONADOS A MEDICAMENTO
EM PACIENTES HOSPITALIZADOS

PALAVRAS-CHAVES:

Drug-related problems, reviews for medication order, hospital, Pharmacist's interventions.

PÁGINAS: 101
GRANDE ÁREA: Ciências da Saúde
ÁREA: Farmácia
RESUMO:

Introduction: Drug-related problems (DRP's) interfere with the patient's optimal therapeutic outcomes and may be associated with increased morbidity, mortality, and health expenditures. Objective: To describe DRPs detected by review of medication orders issued to hospitalized patients in general teaching hospital and to evaluate the acceptability of pharmaceutical interventions by the medical staff. Method: A prospective observational study that included DRPs detected in hospitalized patients during 2016 - 2018 and categorized by the PCNE classification system version 6.2. A descriptive analysis and analysis of the acceptability of pharmaceutical interventions by the medical team was carried out using Stata 15.1 (Stata Corporation, College Station, TX, USA). Results: A total of 3372 DRPs were identified in 15.50% of the patients, corresponding to an incidence of 1.71% patient-days. DRP's of "Treatment Ineffectivity" (1) occurred in 11.5% of cases, "Treatment Costs" DRPs (2) were identified in 5.90% of patients and DRPs classified as "Other" (4) in 2.45% of patients cases. The main causes of DRP's (1) were "inadequate process of use" of the drug, which represented 18.36% and "high duration of treatment" was the most frequent cause of PRD (31% of episodes and incidence of 0.53% - days). In the DRP category (4), the only cause was "inadequacies in the logistics process" (10.91% and 0.19% patient-days). Antimicrobials are implicated in approximately 36% of DRP's, mainly cephalosporins (20.2%), penicillins (6.08%), antidispeticals (38.6%), analgesics and antipyretics (61.2%), propulsives (51.2%), opioids 38.5%) and antiemetics (57.4%). However, of the 3372 interventions performed, 1939 were followed up, of which 36.10% were considered "approved" by the medical team, 21.40% were "not approved" and 42.50% were classified as "unknown". Conclusion: DRPs occur in a high proportion, being ineffective the treatment costs, the most frequent ones caused by inadequacy in the process of use and by prolonged duration of treatment, and the main drugs involved were cephalosporins, penicillin, antidiabetics, analgesics, antipyretics, opioids and antiemetics. The rate of acceptance of pharmaceutical interventions was relatively low; so for an adequate prevention of DRP's the participation of the clinical pharmacists in the wards next to the medical team becomes necessary.

MEMBROS DA BANCA:
Presidente - 1492900 - CICERO FLAVIO SOARES ARAGAO
Externa à Instituição - FRANCISCA SUELI MONTE MOREIRA - UFPE
Externo à Instituição - MIGUEL ADELINO DA SILVA FILHO - F.M.Nassau