Banca de DEFESA: MARIA CLARA DE ARAUJO SILVA CAVALCANTI

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MARIA CLARA DE ARAUJO SILVA CAVALCANTI
DATE: 22/12/2023
TIME: 14:00
LOCAL: Sala de Aulas I GEP/MEJC
TITLE:

Association between 25-hydroxyvitamin D concentrations in pregnant women with preeclampsia and neonatal outcomes.

KEY WORDS:

25-hydroxyvitamin D; Preeclampsia; Neonatal outcomes; Prematurity.

PAGES: 30
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

Preeclampsia is a multifactorial and multisystem disease, specific to pregnancy, which manifests itself in previously normotensive pregnant women after the 20th week of pregnancy. Due to its systemic character, it is associated with maternal, perinatal and neonatal severity situations. Hypovitaminosis D is related to preeclampsia, increases the risk of premature birth, low birth weight, metabolic bone disease, bronchopulmonary dysplasia,  respiratory distress syndrome and neonatal sepsis, suggesting a protective role for this vitamin in the maternal-fetal interface. The aim of the study is to determine the association between 25-hydroxyvitamin D concentrations in pregnant women with preeclampsia and neonatal outcomes. So far, 7 pregnant women and their newborns have been included in the study, whose mothers, aged over 18 years, were previously diagnosed with preeclampsia and were followed up by the research group. Vitamin D was measured by chemiluminescence and data collected from electronic medical records. For statistical analysis, Spearman's aid was applied. For continuous variables, the median value was determined within the interquartile range referring to the 25th and 75th percentiles. P value < 0.05 was considered statistically significant. As the maternal profile data had a mean age of 28.4 years. The pregnant women's body mass index was classified as obese and the average time of sun exposure was 2.7 hours. The mean serum concentration vitamin D in pregnant women was 29.1 ng/mL. All newborns were born by cesarean delivery, 57.1% were female, gestational age and mean birth weight were 35.4 weeks and 2580g, respectively. All RNs were admitted to the MEJC. The mean length of stay in the NICU and in the other wards was 32.3 and 7.4 days, respectively. No deaths were recorded among maternal and neonatal participants. Due to insufficient sample size to date, it has not been possible to correlate maternal vitamin D levels with preeclampsia and neonatal deaths. Thus, the characterization of the sample was carried out.

COMMITTEE MEMBERS:
Externa à Instituição - ANNA CHRISTINA DO NASCIMENTO GRANJEIRO BARRETO - EBSERH
Interna - 1714243 - DANIELLA REGINA ARANTES MARTINS SALHA
Presidente - 1055045 - MARCELA ABBOTT GALVAO URURAHY