Banca de QUALIFICAÇÃO: ANDRÉ ANDERSON COSTA PEREIRA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE : ANDRÉ ANDERSON COSTA PEREIRA
DATA : 19/12/2017
HORA: 09:00
LOCAL: AUDITORIO DO PPGEQ
TÍTULO:

"DEVELOPMENT OF A SYSTEM OF POLYMERIC SOLUTION IN CIRCULATING MEDIUM TO OBTAINING SUBMICROMETRIC PARTICLES"

PALAVRAS-CHAVES:

Atomization; Nanoprecipitation; PMMA; PCL; Preformed polymers; encapsulation.

PÁGINAS: 99
GRANDE ÁREA: Engenharias
ÁREA: Engenharia Química
RESUMO:

Polymeric particles formed on a nanometric scale are of fundamental interest today, especially when used as carrier systems in the controlled release of drugs, cosmetics and nutraceuticals, as well as in the coating of materials with magnetic properties. Therefore, the present study aims to develop a system for the production of nanometric particles of poly (methyl methacrylate) (PMMA) and polycaprolactone (PCL) from the atomization of polymer solution in antisolvent medium. In this system, polymer solutions in different solvents are prepared and atomized in the form of a spray. The droplets generated with the atomization come into contact with an antisolvent liquid that causes the precipitation and formation of the polymeric nanoparticles. In this work, experiments using the proposed system were performed under different operating conditions and the particles obtained were analyzed by Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM). The results showed that it is possible to obtain particles having a size distribution in the 50 to 5000 nm range and that the process variables such as the nature of the polymer, the type of solvent (acetone, ethyl acetate, ethyl alcohol, isopropyl alcohol and propyl alcohol), the atomization pressure (0.25-3 bar) and the temperature of the antisolvent liquid (10-40 °C) directly affect the morphology and the Particle Size Distribution (DTP). In addition, the potential of encapsulation of the proposed system was evaluated. Cotton and ferrite oil was used as material to be encapsulated. Finally, the results of this evaluation were also analyzed in DLS, MET and SEM-FEG, but Fourier Transform Infrared Spectroscopy (FTIR) analyzes were added for encapsulation calibration. According to these results, we can conclude that it is possible to obtain bark and core type polymeric particles with great potential in the application in several areas.

MEMBROS DA BANCA:
Interno - 2929066 - ANDRE LUIS LOPES MORIYAMA
Externo à Instituição - BENTO PEREIRA DA COSTA NETO - IFRN
Interno - 348100 - ELISA MARIA BITTENCOURT DUTRA DE SOUSA
Presidente - 1547970 - JACKSON ARAUJO DE OLIVEIRA