Banca de DEFESA: LEILA JULIANE PINHEIRO DO NASCIMENTO SANTOS

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LEILA JULIANE PINHEIRO DO NASCIMENTO SANTOS
DATE: 08/06/2021
TIME: 09:00
LOCAL: Sala Virtual RUTE do HUOL através do link: https://conferenciaweb.rnp.br/webconf/posgraduacao-huol
TITLE:

CONTRALATERAL SUPPRESSION OF OTOACOUSTIC EMISSIONS BY TRANSIENTS IN BABIES WITH CONGENITAL SYPHILIS

KEY WORDS:

hearing, baby, hearing tests, congenital syphilis, congenital infections

PAGES: 90
BIG AREA: Ciências da Saúde
AREA: Fonoaudiologia
SUMMARY:

Introduction: Syphilis is a global public health problem with complex challenges. In pregnant women, treponema paliidum can be transmitted to the fetus, leading to congenital syphilis, being a risk indicator for hearing loss, as there is evidence of the presence of sensorineural late hearing loss related to vertical transmission to the baby. Based on this premise, the efferent auditory pathway, in particular, the medial olivocochlear region and the outer hair cells, can be assessed by suppressing the otoacoustic supplied by transients, contributing to the identification of the maturation of important physiological processes of this pathway with congenital syphilis. Objective: Study 1 - To characterize the suppression of otoacoustic emissions by transients in children without risk indicators for hearing loss in the first year of life. Study 2 - Analyze the inhibitory effect of contralateral noise on otoacoustic emissions by transients in babies with congenital syphilis. Methodology: Study 1 - Systematic review registered in PROSPERO (nº CRD42020187035). The search took place in the EMBASE, LILACS, LIVIVO, PubMed, Scopus and Web of Science databases. The gray literature included Google Scholar, Open Gray and ProQuest, manual search of references of included studies and consultation with experts. Study 2 - Cross-sectional and prospective study approved by the Research Ethics Committee (nº 3,360,991). The total sample consisted of 35 babies divided into two groups (control -14 babies and study - 21 babies), all of which presented I-III-V waves in the BAEP at 80 dB nNA and wave V at 30 dB nNA and the presence of non-linear TEOAE bilaterally. The suppression analysis was performed using linear TEOAE without noise at 60 dB SPL with white noise contralateral to 60 dB SPL. The mean of inhibition was obtained by subtracting the TEOAE without noise from the TEOAE with noise. Results: Study 1 - 3796 articles were found, after the selection steps 14 studies met the eligibility criteria. All studies showed efferent inhibition in neonates without risk indicators for hearing loss. Suppression was greater in studies that applied non-linear and unfiltered click with averages greater than 1 dB in neonates in the first weeks of life. Study 2 - The study group (SG) showed greater inhibition in RE for the frequency bands from 1.5 to 4KHz. The general amplitudes in both test conditions were higher in the control group (CG), in relation to gender, but they did not present statistical significance. The SG presented 27.8% inhibition ≥ 1 dB and 25% for the CG in the right ear, on the left there was 33.3% ≥ 1 dB in the SG 46.2% in the CG. Conclusion: Study 1 - TEOAE suppression occurs in babies without risk indicators for hearing loss in protocols with different uptake characteristics, generating mean responses that do not allow a normative clinical value so far. Study 2 - The inhibitory effect of contralateral noise on TOAEs of babies with congenital syphilis does not differ from those without risk indicators for hearing loss.

BANKING MEMBERS:
Externa à Instituição - ALESSANDRA SPADA DURANTE - FCMSCSP
Externa à Instituição - RENATA MOTA MAMEDE CARVALLO - UNIFESP
Presidente - 1804274 - SHEILA ANDREOLI BALEN