Introduction: Syphilis is a sexually transmitted disease, which, over the last few years, has had a significant increase in the notification of new cases, bringing an epidemic, especially in developing countries. From 2010 to 2017, there was a sharp increase in the number of new cases of syphilis in the general population in Brazil. Objective: Given this scenario, the objective of this work is to carry out research, applied to the restructuring of epidemiological and hospital intelligence rooms in the country, to promote, improve, and strengthen the technological infrastructure of Health and Environmental Surveillance in Brazil, with a focus on monitoring to face the epidemic of syphilis and other STIs. Methodology: The work was developed in eight stages, and applied in the real world. The first stage was an in-depth analysis of the Term of Decentralized Execution (TED) 111/2017. Subsequently, the addresses to which the equipment for the intelligence rooms should be delivered were mapped. The third stage delved into the theoretical part by conducting a literature review to establish clear and precise objectives for the execution of the work. The fourth part of the study was a consequence of the documentary analysis performed, in which the hypothesis was raised that the spaces available for the installation of the equipment would not be sufficient. In the fifth stage, a situational diagnosis of the spaces destined for the rooms was conducted, and in the sixth stage, all the information and answers to the questionnaire applied were compiled. The seventh stage consists of organizing and setting up a technical committee to discuss the scenarios encountered. Lastly, the equipment of the epidemiological intelligence rooms was resized. Results: Following the step-by-step proposed in the methodology, it was possible to expand the proposal of epidemiological intelligence rooms to a total of 434 spaces, with a 43.72% reduction of the cost involved. This cost reduction made it possible to expand the scope of the project, which also brought local actions in the State of Rio Grande do Norte (RN), through the strengthening of Hospital Surveillance in the State and the implementation and installation of SALUS Situation Rooms in the State of RN, as well as actions in other states of Brazil, the initiative to promote the certification of states and/or municipalities that achieve the goals of eliminating vertical transmission of HIV and/or Syphilis.