Banca de QUALIFICAÇÃO: GUSTAVO BESERRA SOLANO
Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.DISCENTE : GUSTAVO BESERRA SOLANO
DATA : 26/04/2019
HORA: 14:30
LOCAL: Escola Multicampi de Ciências Médicas
TÍTULO:
Visceral Leishmaniasis Canine X Human Visceral Leishmaniasis: Reservoir Control and Early DiagnosisPALAVRAS-CHAVES:
Sandflies, Zoonosis, Prevalence.
PÁGINAS: 41
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
RESUMO:
Visceral leishmaniasis (LV) is a chronic zoonosis, known as an intracellular protozoan of the genus Leishmania, which is one of the most frequent ways to obtain a phlebotomine vector. Canids are considered the nurses' main reservoirs, which are also known as calazar. According to the Ministry of Health, LV lethality increased from 3.4% in 1994 to 5.7% in 2009, which represented an increase of 67.6%. The average lethality in the four-year periods was 5.8% and the Ministry of Health, in the perspective of reducing, has implemented surveillance and patient care actions with LV. However, the measures adopted in them are contrasted with the reality experienced in many cities, such as Caico-RN, where the number of infected persons does not reflect the percentage of diagnosed diseases, suggesting that it is a positive impulse in terms of underestimated beings or an euthanasia. of dogs may not influence the occurrence of infected humans. Therefore, there is an obligation to investigate such questions, so that an euthanasia of animals incapable of transmitting a disease does not happen and the diagnosis of infected but asymptomatic persons is carried out. In this way, we could separate ourselves from the fees with a euthanasia, preserving the relationship between human and male health, and performing the early diagnosis. With this, this project aims to develop and validate a protocol for the early diagnosis of Visceral Leishmaniasis in humans. The specific objectives were to analyze and document epidemiological data in the city from 2011 to 2017, to perform the diagnosis of dogs and humans living in places with animals previously diagnosed with LVC in the neighborhood with the highest prevalence of canine infection in 2017 and to point out the interrelatedness of infected domestic dogs (reservoirs) verses human beings living in the household.This work is a field research with a quantitative approach, with an operational descriptive character. The population of the research will be the dogs and the humans that inhabit the house with canine positivity, of the Neighborhood Frei Damião. Fifty - five dog samples and 30 human samples were collected from households with positive dogs. Initially, dogs were collected from dogs from the neighborhood of Frei Damião, performing the Canine Inquiry, and the biological material was submitted to the TR (Rapid Test) DPP® Visceral Canine-Bio Manguinhos Leishmaniasis. Of the 55 samples, 9 were confirmed by the S7 ELISA test for Visceral Canine Leishmaniasis, a method adopted by the Ministry of Health - MS, carried out at the State Reference Laboratory - LACEN / RN and at these 9 residences. all with negative results. For the detection of LV in humans, the OnSite ™ rapid immunochromatographic test, produced by the company Bio Advance Diagnóstico, was used for human diagnosis by the Unified Health System - SUS, which has already been implanted in some Brazilian states. With this research, it was expected to identify the cases of VL in humans as early as possible, reducing the number of deaths caused by this disease, thus establishing an active search protocol of infected human potential to be treated in a timely manner and serve as base for future changes in the National Program to Combat Leishmaniasis - PCL, MS.
MEMBROS DA BANCA:
Presidente - 2245637 - MICHELLINE DO VALE MACIEL
Interno - 2072824 - MARCELO DOS SANTOS
Externo ao Programa - 3143237 - RAPHAEL RANIERE DE OLIVEIRA COSTA