Banca de DEFESA: ANDRÉ ANDERSON COSTA PEREIRA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
DISCENTE : ANDRÉ ANDERSON COSTA PEREIRA
DATA : 08/02/2018
HORA: 14:00
LOCAL: AUDITORIO DO PPGEQ
TÍTULO:

"DEVELOPMENT OF A SYSTEM OF POLYMERIC SOLUTION IN CIRCULATING MEDIUM TO OBTAINING NANO/MICROMETRIC PARTICLES"

PALAVRAS-CHAVES:

Atomization; Nanoprecipitation; PMMA; PCL; Encapsulation.

PÁGINAS: 105
GRANDE ÁREA: Engenharias
ÁREA: Engenharia Química
RESUMO:

Polymeric particles formed on a nanometric scale are of fundamental interest today, especially when used as carrier systems in the controlled release of drugs, cosmetics and nutraceuticals, as well as in the coating of materials with magnetic properties. Therefore, the present study aims to develop a system for the production of particles of poly (methyl methacrylate) (PMMA) and polycaprolactone (PCL) from the atomization of polymer solution in antisolvent medium. In this system, polymer solutions in different solvents are prepared and atomized in the form of a spray. The droplets generated with the atomization come into contact with an antisolvent liquid which causes the precipitation and formation of the polymer particles. In this work, experiments using the proposed system were performed under different operating conditions and the particles obtained were analyzed by Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM). The results showed that it is possible to obtain particles with nanosphere/nanocapsule and nanofiber characteristics with a size distribution in the range of 50 to 5000 nm. It was also possible to observe that the process variables such as the nature of the polymer, the type of solvent (acetone, ethyl acetate, ethyl alcohol, isopropyl alcohol and propyl alcohol), atomization pressure (0.25-3 bar) and temperature (10-40°C) directly affect the morphology and Particle Size Distribution (PSD). In addition, the potential of encapsulation of the proposed system was evaluated. Cotton oil and ferrite were used as material to be encapsulated. The particles produced in this evaluation were analyzed by DLS, MET and also by Field Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR) and X-ray Diffraction (XRD) for the encapsulation check. According to these results, it was verified the formation of carrier particles, with characteristics of nanocapsules and nanospheres.

MEMBROS DA BANCA:
Presidente - 1547970 - JACKSON ARAUJO DE OLIVEIRA
Interno - 2929066 - ANDRE LUIS LOPES MORIYAMA
Interno - 348100 - ELISA MARIA BITTENCOURT DUTRA DE SOUSA
Externo ao Programa - 1755267 - MARIA CAROLINA BURGOS COSTA DO NASCIMENTO
Externo à Instituição - BENTO PEREIRA DA COSTA NETO - IFRN
Externo à Instituição - THELMA SLEY PACHECO CELLET - UEM